When you say “hot sauce” a lot of people think of McIlhenny’s Tabasco Sauce, which is perhaps the most popular brand.
But it is not the best. McIlhnney’s tabasco sauce has, as its first ingredient, distilled vinegar and that is the predominant taste. Other brands- and they are legion – not only from Louisiana but from places like New Jersey- have cayenne as the primary ingredient, and the vinegar is less pronounced.
I haven’t tried every brand, but in my experience the best is Crystal Hot Sauce; pepper predominates, but the vinegar retains its bite.